"Covid-19 vaccine candidate is 90% effective...brings into view a potential end to the pandemic"

X-Files

X-Files

2
"Covid-19 vaccine candidate is 90% effective, says manufacturer

Interim analysis of vaccine by Pfizer/BioNTech far exceeds expectations of most experts


A vaccine against Covid-19 is in sight, with the announcement of the first interim results in large-scale trials showing the Pfizer/BioNTech candidate is 90% effective, according to the manufacturers, whose analysis shows a much better performance than most experts had hoped for.

The high percentage of those protected makes the findings compelling. Regulators have said they would approve a vaccine that is just 50% effective – protecting half those who get it. The company says there have been no serious side-effects.

“Today is a great day for science and humanity. The first set of results from our phase 3 Covid-19 vaccine trial provides the initial evidence of our vaccine’s ability to prevent Covid-19,” said Dr Albert Bourla, the Pfizer chairman and CEO.

“We are reaching this critical milestone in our vaccine development program at a time when the world needs it most with infection rates setting new records, hospitals nearing over-capacity and economies struggling to reopen.”


The trial will continue until there have been 164 confirmed cases so there is potential for the efficacy rate to change, but a finding that 90% of infections were prevented will excite politicians and public health leaders and brings into view a potential end to the pandemic.

The phase 3 trials have involved more than 43,000 people. People from black and minority ethnic backgrounds appear to have been as well protected as everyone else, the company says.

Gathering the required safety data will take until the third week of November, says the company. The dossier will then be submitted to the regulators for approval. Speedy licensing could mean the first doses being given to healthcare workers by the end of the year.

https://www.theguardian.com/world/2020/nov/09/covid-19-vaccine-candidate-effective-pfizer-biontech
 
mr merlin

mr merlin

EOG Master
Almost 500 medics and academics have penned a letter to U.K. prime minister Boris Johnson - just hours after the U.S. election has been "decided" - informing him that official Covid data is being "exaggerated" and that talk of a second wave of Covid is "misleading".


The letter was critical of the government's handling of the virus and said that the response to the pandemic has been "disproportionate" relative to the risk, according to the Daily Mail.


The group claims that mass testing has "distorted the risk of the virus", that the high numbers of tests are likely to be producing false positives, and that the infection and death rates need to be put into the context of normal seasonal rates.

The group of scientists, medics and academics have also claimed that the U.K.'s second wave "has already peaked":


Professor Tim Spector, who leads the Covid Symptom Study app aiming to track the spread of Covid-19 in the UK, confirmed that there were 'positive signs' the country has 'passed the peak of the second wave'.​

The letter is titled "First Do No Harm". It comes one day after the U.K. confirmed 24,957 positive tests, up 13.9% from the week prior's total. Immunologist Dr. Charlotte R Bell, pediatrician Dr. Rosamond Jones, and Keith Willison, Professor of Chemical Biology at Imperial College are among those who signed the letter.


"The management of the crisis has become disproportionate and is now causing more harm than good," it says. "We urge policy-makers to remember that this pandemic, like all pandemics, will eventually pass but the social and psychological damage that it is causing risks becoming permanent."
 
mr merlin

mr merlin

EOG Master
People waking up to the reality.

Dear Chancellor Dr. Merkel,


We, the signatories, are doctors from all areas of healthcare, who have been serving people in practices and clinics for decades. During this time, we have witnessed more than one seasonal infection in Germany, most of them with far more severe conditions and significantly more deaths than since January 2020 from COVID infectious diseases. Together we serve approx. 70.000 people.






The circumstances of the coronavirus wave in the FRG have been perceived differently than the media and the ongoing warnings of politics, which were unjustified in fact, presented to the public for months. Predictions of individual advisory virologists with millions of seriously ill and hundreds of thousands of deaths in Germany have not been true in any way.


In the practices, hardly any infected patients were infected and if, then with normal, mostly mild progressions of virus flu. The hospitals have been more empty than ever before. There was no overload of ICU. Doctors, doctors and nurses were skillful in short-term work. Initially, we found the wave of the virus running towards us to be threatening and were able to understand the infection protection measures. However, there are months of secured evidence and facts that this wave of the virus is only slightly more intense than an ordinary seasonal flu and must be considered much more harmless than, for example, influenza infection in 2017/2018 with 27.000 deaths in Germany. According to the data situation, there hasn’t been a threat to the German population from Covid-19 for months.


This must be the reason to return to normal life in Germany – a life without restrictions, fear and infection hysteria.


We’re increasingly seeing older people with depression, young children and adolescents with severe anxiety and behavioral disorders, people with severe conditions who could have been cured in timely treatment. We notice disruptions in interpersonal cooperation, hysteria and aggression caused by fear of infection, there are more and more vigilations and denunciations of ′′ positive swab victims ′′ – all this leads to an unprecedented tension and division of the population. The development of additional severe chronic diseases is foreseeable. These diseases with their severe consequences are expected to far outweigh the possible Covid-19 damage in the FRG.


The signatories therefore call on those responsible for health care and politics to discharge their responsibilities for the people of our country and immediately avert this threatening development. We demand an immediate revision of the available data by an independent panel of experts from all relevant specialized groups and a prompt implementation of the resulting consequences for the people of our country.We demand that ineffective and possibly even harmful anti-infection measures be stopped immediately and that mass testing is meaningful (e.g. Currently, 1,1 million tests / week, of which 99,3 % negative, cost per week: EUR 82,5 million) to be audited by a panel of independent experts.


We demand to intensify the protection of risk patients and only from them, where every viral infection can take a dramatic course – the healthy, immune competent population does not need protection beyond the general hygiene and health measures that have been known and proven for generations. Children and adolescents in particular need contacts with viruses to ′′ format ′′ your immune system. Coronavirus has always existed and will continue to exist. Natural immunity is the weapon against it. On the other hand, the mouth-nose cover demanded by politicians does not have a solid scientific foundation
 
B

billysink

EOG Dedicated
mr merlin said:
People waking up to the reality.

Dear Chancellor Dr. Merkel,


We, the signatories, are doctors from all areas of healthcare, who have been serving people in practices and clinics for decades. During this time, we have witnessed more than one seasonal infection in Germany, most of them with far more severe conditions and significantly more deaths than since January 2020 from COVID infectious diseases. Together we serve approx. 70.000 people.






The circumstances of the coronavirus wave in the FRG have been perceived differently than the media and the ongoing warnings of politics, which were unjustified in fact, presented to the public for months. Predictions of individual advisory virologists with millions of seriously ill and hundreds of thousands of deaths in Germany have not been true in any way.


In the practices, hardly any infected patients were infected and if, then with normal, mostly mild progressions of virus flu. The hospitals have been more empty than ever before. There was no overload of ICU. Doctors, doctors and nurses were skillful in short-term work. Initially, we found the wave of the virus running towards us to be threatening and were able to understand the infection protection measures. However, there are months of secured evidence and facts that this wave of the virus is only slightly more intense than an ordinary seasonal flu and must be considered much more harmless than, for example, influenza infection in 2017/2018 with 27.000 deaths in Germany. According to the data situation, there hasn’t been a threat to the German population from Covid-19 for months.


This must be the reason to return to normal life in Germany – a life without restrictions, fear and infection hysteria.


We’re increasingly seeing older people with depression, young children and adolescents with severe anxiety and behavioral disorders, people with severe conditions who could have been cured in timely treatment. We notice disruptions in interpersonal cooperation, hysteria and aggression caused by fear of infection, there are more and more vigilations and denunciations of ′′ positive swab victims ′′ – all this leads to an unprecedented tension and division of the population. The development of additional severe chronic diseases is foreseeable. These diseases with their severe consequences are expected to far outweigh the possible Covid-19 damage in the FRG.


The signatories therefore call on those responsible for health care and politics to discharge their responsibilities for the people of our country and immediately avert this threatening development. We demand an immediate revision of the available data by an independent panel of experts from all relevant specialized groups and a prompt implementation of the resulting consequences for the people of our country.We demand that ineffective and possibly even harmful anti-infection measures be stopped immediately and that mass testing is meaningful (e.g. Currently, 1,1 million tests / week, of which 99,3 % negative, cost per week: EUR 82,5 million) to be audited by a panel of independent experts.


We demand to intensify the protection of risk patients and only from them, where every viral infection can take a dramatic course – the healthy, immune competent population does not need protection beyond the general hygiene and health measures that have been known and proven for generations. Children and adolescents in particular need contacts with viruses to ′′ format ′′ your immune system. Coronavirus has always existed and will continue to exist. Natural immunity is the weapon against it. On the other hand, the mouth-nose cover demanded by politicians does not have a solid scientific foundation
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What is more appropriate here 501 fukk youz or just one blanket fukk you.

Everyone who signed that and the shitstain that posted it got zero cred until I see them licking a toilet seat or sucking each other’s snot.

Nothing worse than a fukkin idiot no life hermit tellin folk how to go about their business. Sormeone need to go bowling with this fukks empty hed
 
blueline

blueline

EOG Master
actual leadership...what a concept

President-elect Joe Biden gave a clear signal on Monday that his administration will take a completely different approach to the coronavirus pandemic — giving a sobering speech warning that the United States would face a "very dark winter," lowering expectations of a rapidly available vaccine, and making an urgent plea for Americans to cover their faces and slow the soaring rate of infection.

Flanked by a masked Vice President-elect Kamala Harris in Wilmington, Del., Biden made early reference to the "positive news" that drugmaker Pfizer had found its vaccine candidate to be more than 90 percent effective. But he said the shot, if approved, "will not be widely available for many months yet to come." In fact, Pfizer announced Monday that the company is aiming to have just 100 million doses ready to distribute in the U.S. by March — enough for only 15 percent of the population.
 
C

Chi_Archie

EOG Veteran
So how does this work? I had the military guy in charge talking during 60 mins, when I was trying to find some winning props ( I didn't) for the TB/NO SNF game.

Only thing that really registered was the logistic difficulties in delivering the 2nd of two dosages.

so we need two separate shots?
 
mr merlin

mr merlin

EOG Master
Chi_Archie said:
So how does this work? I had the military guy in charge talking during 60 mins, when I was trying to find some winning props ( I didn't) for the TB/NO SNF game.

Only thing that really registered was the logistic difficulties in delivering the 2nd of two dosages.

so we need two separate shots?
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This pfizer one is two shots - 3 weeks apart, some of the others that will follow in a month or two are single dose. The two dose vaccine doesn't necessarially mean that you are completely vulnerable until that second dose.
 
X-Files

X-Files

2
"“Based on current projections we expect to produce globally up to 50 million vaccine doses in 2020..."

https://globalnews.ca/news/7450985/pfizer-coronavirus-vaccine-trials-caution-experts/

So no where near enough to vaccinate even the USA, let alone the planet, this year.

With that vaccine each person requires 2 doses.

"“Based on current projections we expect to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021,” the company said (enough to vaccinate 650 million people as it is a double dose)."
 
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Chi_Archie

EOG Veteran
X-Files said:
"“Based on current projections we expect to produce globally up to 50 million vaccine doses in 2020..."

https://globalnews.ca/news/7450985/pfizer-coronavirus-vaccine-trials-caution-experts/

So no where near enough to vaccinate even the USA, let alone the planet, next year.

With that vaccine each person requires 2 doses.

"“Based on current projections we expect to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021,” the company said (enough to vaccinate 650 million people as it is a double dose)."
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not every is going to want it

not everyone needs it (many people already have had it)

This year we will focus on specific populations

Its a very very good start and nothing to be negative

the American and global brain power really did amazing work here under extreme pressure to do an extraordinary thing
 
X-Files

X-Files

2
Chi_Archie said:
not every is going to want it
Click to expand...

No doubt at least 25 million will want it which is the number of people projected to get it this year globally. Even if all 25 million were in the USA that is only a small percentage of the population. So this vaccine is not going to do diddly squat for the world wide epidemic this year. Assuming it is even effective, which is far from a lock at this point (read the entire article i posted a link to).

Chi_Archie said:
not everyone needs it (many people already have had it)
Click to expand...

With vaccines such as this it is recommended generally that everyone needs to & should get it. Since even healthy people can pass the virus from an infection to those who are at "high risk" re serious issues and or death from C-19.

Furthermore just because a person has "had it", i.e. been infected, does not guarantee they can't "have it" again & have serious problems the second time.
 
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Heisenberg

Heisenberg

2
X-Files said:
No doubt at least 25 million will want it which is the number of people projected to get it next year globally. Even if all 25 million were in the USA that is only a small percentage of the population. So this vaccine is not going to do diddly squat for the world wide epidemic next year. Assuming it is even effective, which is far from a lock at this point (read the entire article i posted a link to).



With vaccines such as this it is recommended generally that everyone needs to & should get it. Since even healthy people can pass the virus from an infection to those who are at "high risk" re serious issues and or death from C-19.

Furthermore just because a person has "had it", i.e. been infected, does not guarantee they can't "have it" again & have serious problems the second time.
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X-You’ve been done an excellent job providing Covid information

Thanks
 
C

Chi_Archie

EOG Veteran
50 million doses will be distributed in December, and they are going to have 1.3 billion doses for 2021

Meaning they will have Doses ready to go by the time they run out in the end of 2020.

I don't think you are going to see huge chunks of time where people are waiting for more vaccine to be made. it will be a continuous process
 
X-Files

X-Files

2
[QUOTE="basketcase]
This story reminds me about how scientifically illiterate the media combined with a love of explosive headlines.

The problem is this is a statistical analysis, not a serological one.

The details.
39,000 people in their study have received the two doses, some the vaccine and some placebo.
Of those participants, they so far studied the first 94 people who were symptomatic (asymptomatic people were not tested)
Of those 94, it seems 85 or so were from the placebo group.

From what I understand, no participants were purposefully exposed to the virus 9an ethiocs no-no) so those infected would be from community transmission and this adds a significant extraneous variable into the data.

The correct headline would be "Of the symptomatic participants in Pfizer's study, only 10% were from the vaccine group". That's not exciting enough to draw clicks and doesn't help Pfizer increase its market share of vaccine pre-orders.

I'm still hopeful but the headline is more than a tad misleading.
[/QUOTE]

https://terb.cc/xenforo/threads/pfizer-says-vaccine-trials-90-effective.729642/#post-6863522
 
mr merlin

mr merlin

EOG Master
Chi_Archie said:
50 million doses will be distributed in December, and they are going to have 1.3 billion doses for 2021

Meaning they will have Doses ready to go by the time they run out in the end of 2020.

I don't think you are going to see huge chunks of time where people are waiting for more vaccine to be made. it will be a continuous process
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Those numbers are referring to the pfizer vaccine, there are going to be many approved vaccine's and each will have tens of millions of doses available as time passes. As I've mentioned before this vaccine is not going to be given to children because no children are in the trials - so they cant prove either safety of efficacy of it until they do trails - prob next year. There are approx 250 million adults, at least 60-70 million have already had it, many other wont want the vaccine, at most 150 million will get vaccinated , which is plenty.

A 90% effective vaccine is really, really good, in no way is it disappointing or would it lead to doubts about getting past this pandemic.
 
Bigrunner

Bigrunner

EOG Master
90% is deceiving. Because currently 60% of people infected are already asymptomatic. More work needs to be done to verify how effective the vaccine will be for high risk individuals. Looks promising but more studies need to be completed.
 
FairWarning

FairWarning

Bells Beer Connoisseur
Bigrunner said:
90% is deceiving. Because currently 60% of people infected are already asymptomatic. More work needs to be done to verify how effective the vaccine will be for high risk individuals. Looks promising but more studies need to be completed.
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The bad thing about rushing to be first, you cannot rush the studies.
 
blueline

blueline

EOG Master
Peter Hotez on the Pfizer vaccine:

My understanding of the 90% is it’s all mild infections, they haven’t really seen the impact yet on severe infections and we’d like to see that, so we’ll get that information hopefully over the next few weeks or month or so,” said Hotez.

Hotez adds that this particular vaccine may be challenging to produce if approved for distribution.

“It needs to be stored at -94 degrees Fahrenheit, so that’s going to make it difficult for people in Texas to vaccines where they usually get them...going to Kroger or HEB or CVS or Walgreens,” he said.
 
X-Files

X-Files

2
"Oxford University vaccine is highly effective

The coronavirus vaccine developed by the University of Oxford is highly effective at stopping people developing Covid-19 symptoms, a large trial shows.

Interim data suggests 70% protection, but the researchers say the figure may be as high as 90% by tweaking the dose.

The results will be seen as a triumph, but come after Pfizer and Moderna vaccines showed 95% protection.

However, the Oxford jab is far cheaper, and is easier to store and get to every corner of the world than the other two.

So the vaccine will play a significant role in tackling the pandemic, if it is approved for use by regulators.

"The announcement today takes us another step closer to the time when we can use vaccines to bring an end to the devastation caused by [the virus]," said the vaccine's architect, Prof Sarah Gilbert.

The UK government has pre-ordered 100 million doses of the Oxford vaccine, and AstraZeneca says it will make three billion doses for the world next year.

Prime Minister Boris Johnson said it was "incredibly exciting news" and that while there were still safety checks to come, "these are fantastic results".

continued at:

https://www.bbc.com/news/health-55040635
 
mr merlin

mr merlin

EOG Master
X-Files said:
"Oxford University vaccine is highly effective

The coronavirus vaccine developed by the University of Oxford is highly effective at stopping people developing Covid-19 symptoms, a large trial shows.

Interim data suggests 70% protection, but the researchers say the figure may be as high as 90% by tweaking the dose.

The results will be seen as a triumph, but come after Pfizer and Moderna vaccines showed 95% protection.

However, the Oxford jab is far cheaper, and is easier to store and get to every corner of the world than the other two.

So the vaccine will play a significant role in tackling the pandemic, if it is approved for use by regulators.

"The announcement today takes us another step closer to the time when we can use vaccines to bring an end to the devastation caused by [the virus]," said the vaccine's architect, Prof Sarah Gilbert.

The UK government has pre-ordered 100 million doses of the Oxford vaccine, and AstraZeneca says it will make three billion doses for the world next year.

Prime Minister Boris Johnson said it was "incredibly exciting news" and that while there were still safety checks to come, "these are fantastic results".

continued at:

https://www.bbc.com/news/health-55040635
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Why are you cheering on this vaccine - which appears only ok, when the other two are better?
 
X-Files

X-Files

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mr merlin said:
Why are you cheering on this vaccine - which appears only ok, when the other two are better?
Click to expand...

Why are you posting a strawman remark that i am "cheering" when i did no such thing & in fact made no comment whatsoever. Nil, nada, zilch.

Furthermore, why shouldn't any good news be cause for "cheering". The more effective vaccines the better, eh? Duh.

And, as to your which is "better" remark, did you even read the article.
 
mr merlin

mr merlin

EOG Master
X-Files said:
Why are you posting a strawman remark that i am "cheering" when i did no such thing & in fact made no comment whatsoever. Nil, nada, zilch.

Furthermore, why shouldn't any good news be cause for "cheering". The more effective vaccines the better, eh? Duh.

And, as to your which is "better" remark, did you even read the article.
Click to expand...
It's unlikely that vaccine will ever be widely used here since it's inferior and far behind the others in terms of eventual deployment, they say they might have a few million doses available by year end(mostly in the UK) - big whoop[.
 
X-Files

X-Files

2
mr merlin said:
It's unlikely that vaccine will ever be widely used here since it's inferior and far behind the others in terms of eventual deployment, they say they might have a few million doses available by year end(mostly in the UK) - big whoop[.
Click to expand...

Good Lord, can you even read:

"it will make three billion doses for the world next year."
 
X-Files

X-Files

2
X-Files said:
Good Lord, can you even read:

"it will make three billion doses for the world next year."

-----------------

mr merlin said:
So what, that big talk means shit to us.
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Us? WTF. What a myopic, self-centered, disgusting viewpoint.

Covid is a world wide problem. Not just a "us" me myself & I problem.

mr merlin said:
Are you going to get the vaccine?
Click to expand...

Of course.

But i won't be surprised if an unusually large percentage of covidiot America don't & shoot themselves yet again with yet another covid fuckup.
 
mr merlin

mr merlin

EOG Master
X-Files said:
X-Files said:
Good Lord, can you even read:

"it will make three billion doses for the world next year."

-----------------



Us? WTF. What a myopic, self-centered, disgusting viewpoint.

Covid is a world wide problem. Not just a "us" me myself & I problem.



Of course.

But i won't be surprised if an unusually large percentage of covidiot America don't & shoot themselves yet again with yet another covid fuckup.
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Why do you care? if the vaccine works you have nothing to worry about. I will not get it, at least at first, i'll wait to see if widespread use causes side effects that aren't being reported.
 
X-Files

X-Files

2
mr merlin said:
Why do you care? if the vaccine works you have nothing to worry about. I will not get it, at least at first, i'll wait to see if widespread use causes side effects that aren't being reported.
Click to expand...

Care about...what?

Indications are at least several vaccines are going to work.

They'll be more effective if more people get them.

So i'm going to get it.
 
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cheapseats

EOG Master
Why does it take the frigging government 3+ weeks to approve what science completed in months. It's all laid out for them.
 
mr merlin

mr merlin

EOG Master
cheapseats said:
Why does it take the frigging government 3+ weeks to approve what science completed in months. It's all laid out for them.
Click to expand...
Looks like they dont want to work the holiday., so they're going to wait 3 weeks, have a hearing, and approve it the next day, meanwhile an extra 15000 people will die.

I heard an even more stupid decision, sounds like they will not give the vaccine to the old people that are getting sick and dying first - the very people who if their rate of sickness slowed way down would do the most good, they will waste millions of doses on health care workers and other first responders first.
 
B

billysink

EOG Dedicated
"they"...."I heard"

HTF you do all that with your dick in your ear, a dump in your throat and your 4 skin over your 5 head?


Fukk off inbred.
 
Q

quisp

2
mr merlin said:
Looks like they dont want to work the holiday., so they're going to wait 3 weeks, have a hearing, and approve it the next day, meanwhile an extra 15000 people will die.

/QUOTE]

Now you're showing concern regarding covid deaths? .... I thought you said it was OVER 3, 4, 5 months ago?
Click to expand...
 
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